Ketosis and Ketones: keto X-weight-management
Ketosis is a metabolic state in which your body uses fat as its main source of energy instead of glucose. This happens when you eat very few carbs, such as on a ketogenic diet, or when you fast or starve. When your body doesn’t have enough glucose, it breaks down fat into molecules called ketones, which can be used as fuel by most cells in your body and brain.
Ketones are produced in the liver from fatty acids and have three types: acetone, acetoacetate, and beta-hydroxybutyrate (BHB). BHB is the most abundant and commonly measured ketone in the blood. The level of ketones in your blood reflects how much fat your body is burning and how well you are in ketosis.
Ketosis has many potential benefits for health and weight loss. Some of these include:
Reduced appetite and hunger. Ketones may suppress ghrelin, the hunger hormone, and increase cholecystokinin (CCK), the satiety hormone1.
Enhanced fat burning. Ketosis allows your body to tap into its stored fat for energy, which can help you lose weight2.
Improved blood sugar control. Ketosis lowers insulin levels and increases insulin sensitivity, which can improve blood sugar management in people with diabetes3.
Neuroprotective effects. Ketones may protect the brain from oxidative stress, inflammation, and neurodegeneration, and may also enhance cognitive function and memory .
Anti-inflammatory effects. Ketones may reduce inflammation by inhibiting a protein complex called NLRP3 inflammasome.
However, ketosis is not for everyone and may have some side effects, such as keto flu, bad breath, constipation, muscle cramps, and nutrient deficiencies. To enter and maintain ketosis, you need to follow a very low carb diet that provides enough protein and fat for your needs. You may also need to monitor your ketone levels using urine strips, blood meters, or breath analyzers.
Summary
Ketosis is a metabolic state where your body uses fat and ketones as its main fuel source instead of glucose. It has many potential benefits for health and weight loss, but it also requires careful planning and monitoring.
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